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KMID : 0882420120820010110
Korean Journal of Medicine
2012 Volume.82 No. 1 p.110 ~ p.114
Quadruple Mtachronous Primary Neoplasms in the Aerodigestive Tract
Kim Yong-Hyun

Park Keon-Woo
Lee Soon-Il
Lim Do-Hyoung
Lee Hyun-Suk
Hyun Kyung-Hee
Abstract
Multiple primary neoplasms, defined as the occurrence of multiple malignant neoplasms in the same individual, were first reported by Billroth in 1889. With gradual improvements in diagnostics, and the early detection and effective treatment of malignant neoplasms, the prevalence of multiple primary neoplasms seems to be increasing. Although there have been several reports of triple primary neoplasms in Korea, cases of quadruple neoplasms are rare. Recently, we diagnosed a 69-year-old male with primary neoplasms in the lung, esophagus, vocal cords, and hypopharynx. The authors report this rare case of four metachronous primary neoplasms and provide a review of the literature.
KEYWORD
Multiple primary neoplasms, Aerodigestive tract
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